K, Vijayakumaran Nair Ph.D., M Jayaprakash, R.AshaDevi Ph.D, Suboj Babykutty, Ph.D. ISBN: 978-81-952407-0-8
Sabu Thomas, Abhimanyu Tharayil(eds), Publisher: Elsevier) Pages 97-107, ISBN: 978-0-323-996914
Babykutty, S., A. George, S. Vijayan, S. Sidheek, S. Sulfath, A. Moly, J. Thomas, H. Xavier, P. Chellama, and D. Rajalekshmi.Journal of Applied Pharmaceutical Sciences and Research, Vol. 4, no. 2, Sept. 2021, pp. 21-28, doi:10.31069/japsr.v4i2.5.
Read PublicationIncio J, Ligibel JA, McManus, Suboj P, Jung K, Kawaguchi K, Pinter M, Babykutty S, Chin SM, Vardam TD, Huang Y, Rahbari NN, Roberge S, Wang D, Gomes-Santos IL1, Puchner SB, Schlett CL, Hoffmman U, Ancukiewicz M, Tolaney SM, Krop IE, Duda DG, Boucher Y, Fukumura D, Jain RK. Obesity promotes resistance to anti-VEGF therapy in breast cancer by upregulating IL-6 and potentially FGF-2. Sci Transl Med. 2018 Mar 14;10 (432).
Read PublicationIncio J, Liu H, Suboj P, Chin SM, Chen IX, Pinter M, Ng MR, Nia HT, Grahovac J, Kao S, Babykutty S, Huang Y, Jung K, Rahbari NN, Han X, Chauhan VP, Martin JD, Kahn J, Huang P, Desphande V, Michaelson J, Michelakos TP, Ferrone CR, Soares R, Boucher Y, Fukumura D, Jain RK. Obesity-induced inflammation and desmoplasia promote pancreatic cancer progression and resistance to chemotherapy.Cancer Discov. 2016 May 31; Aug 6 (8): 852-69
Read PublicationIncio J, Tam J, Rahbari NN, Suboj P, McManus DT, Chin SM, Vardam TD, Batista A, Babykutty S, Jung K, Khachatryan A, Hato T, Ligibel JA, Krop IE, Puchner SB, Schlett CL, Hoffmman U, Ancukiewicz M, Shibuya M, Carmeliet P, Soares R, Duda DG, Jain RK, Fukumura D. PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity.Clin Cancer Res. 2016 Jun 15;22(12):2993-3004.
Read PublicationIncio J, Suboj P, Chin SM, Vardam-Kaur T, Liu H, Hato T, Babykutty S, Chen I, Deshpande V, Jain RK, Fukumura D. Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages. PLoS One. 2015 Dec 7;10(12):e0141392.
Read PublicationS. Babykutty, Priya P.S, Nandini.R.J, Suresh Kumar M.A, Mangalam Nair, Priya Srinivas, Srinivas Gopala, Nimbolide retards tumor cell migration, invasion and angiogenesis by down regulating MMP-2/9 expression via inhibiting ERK1/2 and reducing DNA binding activity of NF- κB in colon cancer cells. Mol Carcinog. 2012 Jun; 51(6):475-90.
Read PublicationS. Babykutty, P. Suboj, A. Nair, C. Mohan, P. Srinivas, S. Gopala, Nitric oxide enhances migration/invasion of colon cancer cells by upregulating MMP-2/9 via activation of the cGMP-PKG- ERK signaling pathways. Clinical and Experimental Metastasis. 2012 Jun; 29(5):471-92.
Read PublicationP. Suboj, S. Babykutty, V.G. D. Roshan, R. S. Nair, P. Srinivas, S. Gopala. Aloe emodin inhibits colon cancer cell migration/angiogenesis by downregulating MMP-2/9, RhoB and VEGF via reduced DNA binding activity of NF-kB. European Journal of Pharmaceutical Science. 2012 Apr 11; 45(5): 581-91.
Read PublicationP. Suboj, S. Babykutty, P. Srinivas, S. Gopala. Aloe emodin induces G2/M cell cycle arrest, and apoptosis via activation of caspase- 6 in human colon cancer cells. Pharmacology. 2012; 89:91-98.
Read PublicationS. Babykutty, Jose Padikkala, P. P. Sathiadevan, Vinod Vijayakurup, T. K. Abdul Azis, Priya Srinivas, Srinivas Gopala. Apoptosis induction of centella asiatica on human breast cancer cells. Afr J Tradit Complement Altern Med. 2008 Oct 25; 6(1):9-16.
Read PublicationBabykutty S, Thomas JA, GM AG, Xavier H, Suboj P, Gupta G, PALIT P. Enhancement of immune surveillance in breast cancer by targeting hypoxic tumor endothelium: Can it be an immunological switch point?. Frontiers in Oncology.;13:818.
Read ReviewsSrinivas Gopal, S. Babykutty, Priya Prasanna Sathiadevan, priya Srinivas, Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent. Med Res Rev. 2007 Sep; 27(5): 591-608
Read ReviewsPatil MD, Bhaumik J, Babykutty S, Banerjee UC, Fukumura D. Arginine dependence of tumor cells: targeting a chink in cancer's armor. Oncogene. 2016 Apr 25. doi: 10.1038/onc.2016.37, [Epub ahead of print].
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